Findings suggest a role for modulation of the callosal system with subcortical or cortical epileptic discharges in hypsarrhythmia and infantile spasms

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Abstract

OBJECTIVE:

We analyzed the features of fast oscillations (FOs) and connectivity in hypsarrhythmia to identify biomarkers for predicting seizure outcomes after total corpus callosotomy (TCC) in children with pharmacoresistant infantile spasms (IS). We hypothesize that the power of FOs and connectivity of slow waves in hypsarrhythmia would indicate the prognosis of IS.

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