Cognitive but not motor symptoms predict transition to dementia in motoric cognitive risk syndrome

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  • The severity of cognitive but not motoric status at the time of diagnosis of motoric cognitive risk syndrome (MCR) is a predictor of transition to dementia.

Why this matters

  • MCR, characterized by cognitive complaints and slow gait, is a predictor of major cognitive decline and dementia. It is unknown whether the cognitive or motor element of the syndrome has the greater influence on transition to dementia. Such information would facilitate assessment of dementia risk and development of therapies.

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